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Basics

Name Benjamin Lewis
Label Senior Scientist | Multi-Omic Discovery
Email benlewis.biology @ gmail.com
Url https://gitbenlewis.github.io/
Summary Neuro-data scientist specializing in multi-omic biomarker discovery, integrative transcriptomics, and therapeutic target identification in biotech R&D.

Work

  • 2026.01 - Present

    San Diego, CA

    Senior Scientist - Bioinformatics, Research and Development
    Actio Biosciences
    Promoted to Senior Scientist in January 2026 in recognition of scientific leadership, cross-program impact, and strategic contributions to portfolio advancement.
    • Partnered with biology, translational, and executive stakeholders to guide data-driven portfolio decisions.
    • Led multi-omic biomarker discovery and novel target identification across therapeutic programs.
    • Drove target identification efforts resulting in multiple assets advancing to nomination and portfolio prioritization.
    • Scientific lead for single-cell and bulk transcriptomic strategy across multiple therapeutic programs.
    • Designed and deployed a production-grade RNA-seq pipeline (Nextflow, Python, AWS), reducing turnaround time from 2 weeks to <48 hours and standardizing analytics across R&D.
  • 2024.04 - 2025.12

    San Diego, CA

    Bioinformatics Scientist II, Research and Development
    Actio Biosciences
    Multi-omic biomarker discovery and integrative transcriptomics supporting early-stage therapeutic programs.
  • 2022.04 - 2024.03

    San Diego, CA

    Scientist I, Research and Development
    Aspen Neuroscience
    Cross-functional single-cell and multiomic discovery supporting pipeline and IND-enabling programs.
    • Single-cell transcriptomics/multiomics: project design and data analysis lead.
    • Functional genomics for pipeline development: project design and data analysis lead.
    • Contributed to preclinical and IND-enabling studies to support regulatory filings and clinical progression.
  • 2013.06 - 2013.12

    Santa Maria, CA

    Research and Development Intern
    Hardy Diagnostics
    Developed chromogenic diagnostic media formulations and authored protocols for 510(k) validation studies.

Education

  • 2016.09 - 2022.03

    San Diego, California, USA

    PhD
    University of California, San Diego
    Molecular Biology
    • Quantitative Methods in Genetics and Genomics
    • Statistical Methods in Bioinformatics
  • 2013.09 - 2015.06

    San Luis Obispo, California, USA

    Master of Science (MS)
    California Polytechnic State University
    Stem Cell Research
  • 2008.09 - 2013.06

    San Luis Obispo, California, USA

    Bachelor of Science (BS)
    California Polytechnic State University
    Biochemistry and Microbiology (Double Major)

Publications

Skills

Bioinformatics and Statistical Analysis
Multiomic data analysis (Single-cell transcriptomics, Proteomics, ATAC-seq, CLIP-seq)
Predictive machine learning model design and implementation
Data visualization and statistical analysis
Programming and Computational Skills
Python (pandas, matplotlib, seaborn, scikit-learn, scanpy/adata, scvi-tools, PyTorch)
Linux
AWS and Cloud/High-Performance Computing Environments
GitHub
R
Nextflow-based RNAseq pipelines
Molecular Biology
Viral vector design and production
Gene cloning and DNA assembly techniques
NGS/qPCR analysis
RNA manipulation and analysis techniques
Immunoblotting
Cellular Biology and Analysis
CRISPR/Cas9 gene editing in iPSCs and cell lines
Stem cell-based disease modeling
Extracellular flux analysis
Flow cytometry techniques and analysis (FACS)
Live cell imaging
Microscopy and Imaging
Immunofluorescence microscopy
Confocal microscopy
Brightfield microscopy
Plate scanning

Languages

English
Native speaker